Scientific HIV research in Africa and the Middle East: a socio-economic demographic analysis

Background: In Africa, HIV/AIDS analysis is concentrated in sure nations, notably South Africa. This distribution might not precisely replicate the illness prevalence or the true analysis efforts of nations. Aims: To establish HIV/AIDS analysis productiveness of nations in Africa and the Center East, in absolute phrases and adjusted for individuals dwelling with HIV, inhabitants dimension and financial growth. Strategies: We recognized all of the articles and opinions on HIV and AIDS within the Internet of Science Core Assortment through which African or Center Jap nations had participated. After figuring out the variety of paperwork produced by every nation, we adjusted the findings for the variety of individuals dwelling with HIV, variety of inhabitants, gross home product and gross nationwide revenue per capita. 

 African and Center Jap nations participated in 21.52% (n = 14 808) of all 68 808 paperwork analysed. East and Southern Africa produced 17.8% of all paperwork (n = 12 249), West and Central Africa accounted for under 3.34% (n = 2300), and the Center East and North Africa, 1.18% (n = 814). South Africa produced 40.94% (n = 6 063) of all publications. Solely two different African nations – Uganda (12.97%; n = 1 921) and Kenya (10.71%; n = 1 586) – produced greater than 10% of those publications. The indices used for adjusting analysis productiveness revealed the hassle and contribution of different nations. Conclusion: Our examine confirmed the main function of South Africa in driving HIV/AIDS analysis, but additionally highlighted the contribution of nations corresponding to Uganda, Malawi, Botswana, Zimbabwe and Mozambique.

In complete, 75 articles have been chosen. There was a rise within the variety of SRs on CBCT from 2014 onwards, as 83% of the SRs on this matter have been printed after 2013, and 72% between 2016 and up to now. Twenty SRs (27%) carried out meta-analysis. Solely 28% of the SRs supplied an in depth description of CBCT protocols. In response to SR proof, virtually all specialties of dentistry have superior concomitantly with the introduction of CBCT. Nearly all of SRs have been associated to medical purposes (degree 2 of efficacy), adopted by technical parameters (degree 1 of efficacy).

Just some CBCT fashions have been talked about within the SRs chosen. Over the course of twenty years, SRs associated to CBCT purposes for a broad vary of dental specialties have been printed, with the overwhelming majority of research at ranges 1 and a pair of of diagnostic efficacy. Not all fashions accessible in the marketplace have been scientifically validated. Always, one ought to stay cautious as such to not merely extrapolate in vitro outcomes to the medical setting. Additionally, contemplating the big variety of CBCT gadgets and protocols, reported outcomes shouldn’t be overstated or generalized, as outcomes typically confer with particular CBCT gadgets and protocols.

Bibliometric Evaluation of International Scientific Analysis on COVID-19

For the reason that outbreak of coronavirus illness 2019 (COVID-19), a lot of COVID-19-related studies have been printed in journals or submitted to preprint platforms. On this examine, we search the COVID-19-related literature formally printed and included within the Internet of Science (WOS) database or submitted to 4 preprint platforms: bioRxiv, medRxiv, Preprints, and SSRN. Utilizing knowledge on the variety of studies, creator establishment, nation, and analysis class, we analyze international tendencies in COVID-19 analysis, together with establishment distribution and analysis hotspots. The outcomes present that a lot of COVID-19-related studies have been produced; america has contributed probably the most printed literature, adopted by China.

America has additionally printed probably the most studies included within the WOS within the classes of non-pharmaceutical interventions, therapy, and vaccine-related studies, whereas China has printed probably the most literature within the classes of medical options and issues, virology and immunology, epidemiology, and detection and prognosis. Publication nations are concentrated in Asia, North America, and Europe, whereas South America and Africa have much less literature. In conclusion, many scientific analysis points associated to COVID-19 should be additional clarified and COVID-19 analysis urgently wants international cooperation.

Scientific HIV research in Africa and the Middle East: a socio-economic demographic analysis

Standardized Definitions for Analysis of Coronary heart Failure Therapies: Scientific Professional Panel From the Coronary heart Failure Collaboratory and Tutorial Analysis Consortium

The Coronary heart Failure Tutorial Analysis Consortium is a partnership between the Coronary heart Failure Collaboratory (HFC) and Tutorial Analysis Consortium (ARC), comprised of main coronary heart failure (HF) educational analysis investigators, sufferers, United States (US) Meals and Drug Administration representatives, and trade members from the US and Europe. A collection of conferences have been convened to ascertain definitions and key ideas for the analysis of HF therapies together with optimum medical and machine background remedy, medical trial design parts and statistical ideas, and examine endpoints.

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This manuscript summarizes the professional panel discussions as consensus suggestions centered on populations and endpoint definitions; it isn’t exhaustive or restrictive, however designed to stimulate HF medical trial innovation. Murray Sidman’s (1960) Ways of Scientific Analysis: Evaluating Experimental Information in Psychology simply celebrated its sixtieth anniversary. It’s doubtless one of the vital influential books within the historical past of Conduct Evaluation. This evaluation outlines the rationales for, and particulars of, strategies for the investigation of the habits of particular person topics that Sidman offered. Lots of his observations and proposals are as well timed as ever, perhaps much more so, given the “reproducibility disaster” and certainly one of its main origins.