Maand: mei 2020

From laboratory bench to benchmark: technology transfer in laboratory medicine.

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From laboratory bench to benchmark: technology transfer in laboratory medicine.

Life Sciences research, improve the innovation, able to influence clinical decision making, both in diagnosis and therapy. Indeed, from the knowledge of the special needs and demands of the technical-scientific, researchers were able to contain and experiment innovative solutions. Despite these strengths, transferring research to the market in the Life Sciences shows criticalities enough.

The purpose of this paper is to provide concrete evidence of the technology transfer process based on the exploitation of the results obtained by KronosDNAsrl, an academic spin-off focusing on reproductive medicine.


method
Different tools are used to evaluate the technical feasibility (validation of the results obtained with the prototype) and to manage the process of technology transfer from One4Two®.


result
Different analyzes we conducted demonstrated the feasibility of the proposed solution. As a result, a prototype has been developed and validated One4Two®.


conclusion
Here, we provide evidence of how the power of knowledge acquired translational research on the “bench” can be used to transfer to the market on a “benchmark” allows innovation in Laboratory Medicine. In addition, the model described for One4Two® can be easily transferred to other products.

From laboratory bench to benchmark: technology transfer in laboratory medicine.
From laboratory bench to benchmark: technology transfer in laboratory medicine.

Scientific integrity among nursing students participating in the Scientific Initiation Program: An exploratory study.

To determine the position and practice adopted by nursing students in scientific initiation program on the principles of scientific integrity in various stages of the process of doing science.An quantitative exploratory study, in which participants from the nursing students Scientific Initiation Program of the federal District interviewed.

Fifty (50) nursing students participated in the study. Most participants were interviewed presented a good understanding of the process of doing research in different stages. However, it was found that although they were familiar with the practices of good science, students do not always behave in the most responsible way.

It was observed that the knowledge on topics related to the ethics of the scientific process is mainly obtained through formal education, which consists of classes and courses. Nevertheless, the importance of complementary spaces such as study and research groups recognized.

Conclusion: Research experience that education and vocational training room are important for students. Hence, good research practice need to be incorporated at the beginning of the academic curriculum.

The scientific literature on Coronaviruses, COVID-19 and its associated safety-related research dimensions: A scientometric analysis and scoping review.

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The scientific literature on Coronaviruses, COVID-19 and its associated safety-related research dimensions: A scientometric analysis and scoping review.

The COVID-19 global pandemic has resulted in an abundance of quick research follows an outbreak. In just a few months, more than a thousand studies on this topic have appeared in the scientific literature.

In this brief review, we analyze the bibliometric aspects of this study at the macro level, as well as those dealing with coronavirus in general. In addition, through analysis of the scope of the literature on COVID-19, we identify the dimensions associated with the main safety that these studies have so far dealt with.

Our findings show that in various domains of research, and in spite of the medical aspects and clinical safety of vaccines and treatments, issues related to transport safety of patients, safety of health professionals, biosafety laboratories and facilities, social security, food security, and especially mental / psychological health and safety in the country have so far attracted the most attention from the scientific community in relation to the 19th COVID pandemic.

Our analysis also revealed a variety of potentially significant safety problems caused by global health emergency that now has attracted scientific attention only limited but may require more attention. This includes things such as cyber security, economic security, and the security of the supply chain.

These findings highlight why, from the perspective of academic research, interdisciplinary approach is holistic and collective scientific efforts needed to help understand and mitigate the effects of this crisis are safety implications reach far beyond bio-medical risk. holistic scientific understanding of salvation as COVID-19, the next crisis could be an instrument to be better prepared for a pandemic in the future.

The scientific literature on Coronaviruses, COVID-19 and its associated safety-related research dimensions: A scientometric analysis and scoping review.
The scientific literature on Coronaviruses, COVID-19 and its associated safety-related research dimensions: A scientometric analysis and scoping review.

Ten simple rules for running a successful women-in-STEM organization on an academic campus.

Academic culture faced by women in science, technology, engineering and math (STEM) in the United States has triggered the formation of groups of grassroots advocacy to empower women scientists in training.

However, the impact of these initiatives often measured and underappreciated. Our Women in Science and Engineering organization (WiSE) function postdoctoral researchers, graduate students and research technicians (trainee) in a private research institute for biological sciences.

Here we propose the following guidelines to foster women-in-STEM-focused groups based on a survey of our own scientific community as well as the experience of our group leader WiSE success. We hope these recommendations can provide guidance to the advocacy group in research and other academic organizations who want to strengthen their efforts.

While our own group is specifically focused on the country represented women in science, we hope this guide can be adapted and applied to groups that advocate for minorities in the scientific community that is larger (ie, those of gender, race / ethnicity, background socio- economic, sexual orientation, etc.).

Forensic epistemology: A need for research and pedagogy.

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Forensic epistemology: A need for research and pedagogy.

This is the third in a series of articles reporting the forensic epistemology. Our first two research articles presenting scientific results based on experimental design; including quantitative and qualitative feedback from forensic science practitioners to scenarios and evidence.

Based on a synthesis of these studies there is no evidence of the knowledge gaps in formal reasoning for some forensic practitioners, and limited understanding of a specific case study. Combining these results with a review of the current literature in the field of forensic reasoning, we now offer evidence of teaching and research strategies that can help improve the status of epistemic (belief, and justification of knowledge) forensic science claims.

This paper focuses on a review of narrative integrated using hermeneutic methods of analysis to identify: (i) the epistemic state of forensic science; (Ii) strategies to increase knowledge; (Iii) the need for cooperation between practitioners and academics; and, (iv) an area for future research.

Forensic epistemology: A need for research and pedagogy.
Forensic epistemology: A need for research and pedagogy.

Enquête sur la certification aux bonnes pratiques cliniques en recherche académique.

Good clinical practice (GCP) is a scientific and ethical international quality standards for the design, conduct, performance, monitoring, auditing, recording, analysis and reporting of clinical trials. Before starting a clinical trial, researchers are committed to conducting research in accordance with GCP, disposition rules and protocols.

The sponsor is responsible for selecting researchers and to control their skills. While the industry sponsors systematically require GCP training certificates, academic sponsorship appears to be less demanding. We have conducted two surveys between April and June 2018.

The first questionnaire was sent to 40 French academic direction of clinical research and innovations to determine their needs about GCP training of the researchers who participated in their trial.

The second questionnaire is transmitted to a doctor of “Bretagne Recherche Clinique hospitalière network”: Rennes, Saint-Malo, Saint-Brieuc, Vannes, Lorient and Pontivy hospital, to determine the level of GCP certification, and their needs in terms of clinical research training. Twenty-eight (70%) responded to the survey direction of the first clinical study, of whom 18 (64%) required GCP certification systematic researchers in the case of category 1 studies of interventions. this rate decreased to category 2 (50%) and non-intervention category 3 (18%) of the study.

A total of 345 doctors answered the second survey, of which 263 (76%) had ever clinical trial investigators. However, only 29% of all physicians and 54% of those who had been the principal investigator has been certified for GCP training. These results support the need for a large campaign GCP training in public hospitals.